Max Delbrück Center MDC - Max-Delbrück-Centrum für molekulare Medizin in der Helmholtz-Gemeinschaft

Our Research

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms of health and disease, and translate those findings into medical practice.

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Data Science and Artificial Intelligence

Enabling multi-modal prediction from molecules to cohorts.

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Research Highlights

Our research teams publish around 450 specialist articles every year. Our research highlights can be found here, presented in a comprehensible format.

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Selection of research highlights
induced pluripotent stem cells in a pluripotency test

Research News & Events

woman
Science

Agnieszka Rybak-Wolf wins Alzheimer‘s research grant

How do the ApoE4 gene variant and the herpes simplex virus work together to increase the risk of developing Alzheimer’s disease? Agnieszka Rybak-Wolf has been awarded a grant from Stiftung Alzheimer Initiative to study the molecular interaction between the two risk factors.
man
Science

In Memoriam: Peer Bork

We mourn the sudden unexpected loss of Peer Bork, a formative figure who helped shape the center’s intellectual spirit and commitment to innovative life science. Bork went on to build an extraordinary international career, influencing modern biology far beyond Berlin.
Nikolaus Rajewsky und Leif Sander
Science

A new opportunity for Berlin

The Einstein Center for Early Disease Interception has been funded with six million euros. In an interview, Nikolaus Rajewsky and Leif Erik Sander, both spokespeople of the center, explain why new technologies and cross-institutional collaboration will make disease prevention in the future possible.
People talking
Science

Bridging science and business

During the Predictive Systems Medicine Partnering Event at the Max Delbrück Center, researchers and industry representatives shared insights and explored commercialization opportunities – advancing our mission to turn discovery into real-world health impact.
Scientific image
Science

Berlin joins national genome data network

The Max Delbrück Center and Berlin Institute of Health at Charité have joined a national network of six Genome Data Centers and the German Human Genome-Phenome Archive, adding Berlin as an operational data hub for genomic medicine and omics-based research.
Ines Lahmann and Mina Gouti
Science

A spin-off targeting neuromuscular disorders

A team led by Mina Gouti has developed a stem cell-based model that enables researchers to test new drugs to treat neuromuscular diseases and to refine existing therapies. The project, called NMJCare, was named one of the top ten ideas in the national Science4Life start-up competition.
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Science

Building environmentally friendly labs

The Max Delbrück Center has recently completed construction of a new Demonstrator Lab as a testbed to reduce the environmental impact of biomedical research. The insights gained will be applied to all new building renovations across the center.
Karen Christman
Science

Karen Christman receives Humboldt Research Award

Karen Christman, a Stiftung Charité Visiting Fellow at the Max Delbrück Center, is among the first researchers to have won a Humboldt Research Award under Germany’s Global Minds Initiative. The award will enable her to expand her research in Germany on bioengineering.
Scientific Image

Observing synapses in action

Jana Kroll, Christian Rosenmund and their teams have captured the fleeting moment a nerve cell releases its neurotransmitters into the synaptic cleft. The work was published in “Nature Communications.”

All News & Events

Publications

FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells

Journal of Experimental Medicine

Serum amyloid A in HFpEF and cardiometabolic diseases

Basic Research in Cardiology

Rapamycin exerts its geroprotective effects in the ageing human immune system by enhancing resilience against DNA damage

Aging Cell

Improving cardiovascular risk stratification through the derivation and validation of an elevated triglyceride-glucose index

Diabetes Obesity and Metabolism

All Publications