Science April 10, 2006 Sleeping Beauty transposase modulates cell-cycle progression through interaction with Miz-1 Transposable elements (transposons) are segments of DNA with the ability to move from one location...
Science March 23, 2006 Cardiac hypertrophy in transgenic rats expressing a dominant negative mutant of the natriuretic peptide receptor B The family of natriuretic peptides (NP) consists of the structurally homologous but genetically...
Science March 17, 2006 Running in pregnancy transiently increases postnatal hippocampal neurogenesis in the offspring Activity influences brain anatomy and function across the lifespan of the individual. While it is...
Science March 08, 2006 NF- κB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiaion hair placode down growth The transcription factor, NF- κB, is required for normal development of epidermal appendages...
Science March 02, 2006 Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma Hodgkin lymphoma (HL) is characterized by the malignant growth of the so-called Hodgkin/Reed...
Science January 25, 2006 Natural variation and genetic covariance in adult hippocampal neurogenesis Adult neurogenesis refers to the neuronal development within the adult brain- a process which is...
Science December 06, 2005 Heart and soul/PRKCi and nagie oko/Mpp5 regulate myocardial coherence and remodeling during cardiac morphogenesis. Organ morphogenesis requires cellular shape changes and tissue rearrangements that occur in a...
Science November 15, 2005 Histone H3-tail positioning and acetylation by the c-Myb but not the v-Myb DNA binding SANT domain The production of blood cells, including erythrocytes, granulocytes, macrophages, and immune cells...
Science October 17, 2005 Ubx2 links the Cdc48 complex to ER-associated protein degradation The secretory pathway of eukaryotic cells harbors an elaborate protein quality control system, which...
Science September 30, 2005 A human protein-protein interaction network: the first step towards a human interactome map The sequencing of the human genome has provided a surprisingly small number of genes, indicating that the complex organization of life is not reflected in the gene number but, rather, in the gene products – that is, in the proteins.